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I hear men can get breast cancer too. What gives men the highest risk of getting breast cancer?

Men can indeed get breast cancer but their risk of developing breast cancer is several hundred times lower than women. However, the men with the highest risk of developing breast cancer are those with Kleinfelter’s syndrome – a common genetic disease affecting about 1 in 1,000 to 1 in 1,500 males.
Males usually have two sex chromosomes: XY but those with Kleinfelter’s syndrome males have an extra X chromosome making them XXY. The gynecomastia (breast development) of the males with Kleinfelter’s make them much more likely to develop breast cancer than those with other causes of gynecomastia (obesity, liver failure, etc.).